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CL 218872

CAS No. 66548-69-4

CL 218872 ( —— )

产品货号. M22192 CAS No. 66548-69-4

CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptors respectively).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥316 有现货
25MG ¥680 有现货
50MG ¥1191 有现货
100MG ¥2001 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    CL 218872
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptors respectively).
  • 产品描述
    CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    GABAA
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    66548-69-4
  • 分子量
    278.23
  • 分子式
    C13H9F3N4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:13.9 mg/mL (50 mM; Need ultrasonic)
  • SMILES
    Cc1nnc2ccc(nn12)-c1cccc(c1)C(F)(F)F
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Wang B , Lv K , Liu H , et al. Contribution of the α5 GABAA receptor to the discriminative stimulus effects of propofol in rat[J]. Neuroreport, 2018:347-352.
产品手册
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